OncRef

Clinical Trial: NCT04151940

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

Status:

RECRUITING

Phase:

Not Applicable

Lead Sponsor:University of Washington
Information Provided By:University of Washington
Last Update Posted:2026-08-06

Study Overview

Brief Summary

This study investigates the changes in positron emission tomography (PET)/computed tomography (CT) imaging scans during chemoimmunotherapy and radiation therapy treatment in patients with stage IV non-small cell lung cancer. Analyzing changes in PET/CT imaging scans may help doctors assess and predict patterns of cancer response to chemoimmunotherapy and radiation therapy.

Official Title

An Interventional Study of PET/CT Changes During Chemoimmunotherapy and Radiation Therapy for Patients With Metastatic NSCLC (PET Bright)

Conditions

Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8

Intervention / Treatment

  • Procedure: Positron Emission Tomography
  • Procedure: Computed Tomography
  • Drug: Chemotherapy
  • Biological: Immunotherapy
  • Radiation: Radiation Therapy
  • Procedure: Biospecimen Collection
  • Procedure: Magnetic Resonance Imaging

Other Study ID Numbers

  • RG1005458
  • NCI-2019-07068
  • 10203
  • R01CA258997

Start Date (Actual)

2019-09-26

Primary Completion Date (Estimated)

2027-11-30

Study Completion Date (Estimated)

2027-11-30

Enrollment (Estimated)

80

Study Type

Interventional

Phase

Not Applicable