Clinical Trial: NCT05341492
EGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer
Status:
RECRUITINGPhase:
Early Phase 1| Lead Sponsor: | Second Affiliated Hospital of Guangzhou Medical University |
| Information Provided By: | Second Affiliated Hospital of Guangzhou Medical University |
| Last Update Posted: | 2024-06-25 |
Study Overview
Brief Summary
This study is a single-arm, open, exploratory clinical study to evaluate the safety and efficacy of EGFR/B7H3 CAR-T in patients with EGFR/ B7H3-positive advanced solid tumors (lung cancer and triple-negative breast cancer)
Official Title
A Single-arm, Open, Exploratory Clinical Study Evaluating the Safety and Efficacy of EGFR/B7H3 CAR-T in Patients With EGFR/ B7H3-positive Advanced Solid Tumors (Lung and Triple-negative Breast Cancer)
Conditions
EGFR/ B7H3-positive Advanced Lung Cancer, EGFR/ B7H3-positive Advanced Triple-negative Breast Cancer
Intervention / Treatment
- Biological: EGFR/B7H3 CAR-T
Other Study ID Numbers
- ZZBGCART-016
Start Date (Actual)
2022-05-01
Primary Completion Date (Estimated)
2030-05-01
Study Completion Date (Estimated)
2035-05-01
Enrollment (Estimated)
30
Study Type
Interventional
Phase
Early Phase 1
| Lead Sponsor: | Second Affiliated Hospital of Guangzhou Medical University |
| Information Provided By: | Second Affiliated Hospital of Guangzhou Medical University |
| Last Update Posted: | 2024-06-25 |
Study Overview
Brief Summary
This study is a single-arm, open, exploratory clinical study to evaluate the safety and efficacy of EGFR/B7H3 CAR-T in patients with EGFR/ B7H3-positive advanced solid tumors (lung cancer and triple-negative breast cancer)
Official Title
A Single-arm, Open, Exploratory Clinical Study Evaluating the Safety and Efficacy of EGFR/B7H3 CAR-T in Patients With EGFR/ B7H3-positive Advanced Solid Tumors (Lung and Triple-negative Breast Cancer)
Conditions
EGFR/ B7H3-positive Advanced Lung Cancer, EGFR/ B7H3-positive Advanced Triple-negative Breast Cancer
Intervention / Treatment
- Biological: EGFR/B7H3 CAR-T
Other Study ID Numbers
- ZZBGCART-016
Start Date (Actual)
2022-05-01
Primary Completion Date (Estimated)
2030-05-01
Study Completion Date (Estimated)
2035-05-01
Enrollment (Estimated)
30
Study Type
Interventional
Phase
Early Phase 1