Clinical Trial: NCT06267001
A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy
Status:
TERMINATEDPhase:
Phase 3| Lead Sponsor: | Hoffmann-La Roche |
| Information Provided By: | Hoffmann-La Roche |
| Last Update Posted: | 2026-06-10 |
Study Overview
Brief Summary
The purpose of this study was to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab administered to participants with non-small cell lung cancer (NSCLC) following resection and adjuvant chemotherapy.
Official Title
A Phase III, Randomized, Double-blind Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Stage IIB, IIIA, or Select IIIB, PD-L1 Positive, Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy
Conditions
Non-small Cell Lung Cancer (NSCLC)
Intervention / Treatment
- Drug: Atezolizumab
- Drug: Tiragolumab
- Drug: Placebo
Other Study ID Numbers
- GO45006
- 2023-506696-10-00
- 2023
Start Date (Actual)
2024-03-21
Primary Completion Date (Actual)
2025-12-16
Study Completion Date (Actual)
2025-12-16
Enrollment (Actual)
56
Study Type
Interventional
Phase
Phase 3
| Lead Sponsor: | Hoffmann-La Roche |
| Information Provided By: | Hoffmann-La Roche |
| Last Update Posted: | 2026-06-10 |
Study Overview
Brief Summary
The purpose of this study was to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab administered to participants with non-small cell lung cancer (NSCLC) following resection and adjuvant chemotherapy.
Official Title
A Phase III, Randomized, Double-blind Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Stage IIB, IIIA, or Select IIIB, PD-L1 Positive, Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy
Conditions
Non-small Cell Lung Cancer (NSCLC)
Intervention / Treatment
- Drug: Atezolizumab
- Drug: Tiragolumab
- Drug: Placebo
Other Study ID Numbers
- GO45006
- 2023-506696-10-00
- 2023
Start Date (Actual)
2024-03-21
Primary Completion Date (Actual)
2025-12-16
Study Completion Date (Actual)
2025-12-16
Enrollment (Actual)
56
Study Type
Interventional
Phase
Phase 3